Staff profile
Overview
https://internal.durham.ac.uk/images/profiles/17979/ExequielPortaDurhamUniversity.jpg
| Affiliation | Room number | Telephone |
|---|---|---|
| COFUND Fellow in the Department of Chemistry |
Research interests
- Medicinal Chemistry
- Activity-based proteomics
- Bioorganics
- Kinases
- Neglected Tropical Diseases
Media Contacts
Available for media contact about:
- Biological and Biomedical Sciences:
- Bioactive chemistry:
- Infectious diseases:
- Chemistry:
- Structure, Property and Function:
Publications
Journal Article
- Porta, Exequiel O. J., Isern, Jaime A., Kalesh, Karunakaran & Steel, Patrick G. (2022). Discovery of Leishmania Druggable Serine Proteases by Activity-Based Protein Profiling. Frontiers in Pharmacology 13: 929493.
- Porta, Exequiel, Wilkinson, Shane, Ballari, María Sol, Tekwani, Babu & Labadie, Guillermo (2021). Systematic study of triazolyl sterols for the development of new drugs against parasitic Neglected Tropical Diseases. European Journal of Medicinal Chemistry
- Díaz-Storani, Luz, Clary, Anaelle A., Moreno, Diego M., Ballari, María Sol, Porta, Exequiel O.J., Bracca, Andrea B.J., Johnston, Jonathan B. & Labadie, Guillermo R. (2021). Synthesis and interaction of terminal unsaturated chemical probes with Mycobacterium tuberculosis CYP124A1. Bioorganic & Medicinal Chemistry 44: 116304.
- Porta, Exequiel O. J., Ballari, María Sol, Padrón, José M. & Labadie, Guillermo R. (2021). Lipophilic Salirasib analogs with enhanced antiproliferative activity against human solid tumor cell lines. ChemMedChem
- Jäger, Sebastián N., Porta, Exequiel O.J. & Labadie, Guillermo R. (2019). Convenient synthesis of the immunogenic glycolipid BbGL1. Steroids 141: 41.
- Porta, Exequiel O. J., Bofill Verdaguer, Ignasi, Perez, Consuelo, Banchio, Claudia, Ferreira de Azevedo, Mauro, Katzin, Alejandro M. & Labadie, Guillermo R. (2019). Repositioning Salirasib as a new antimalarial agent. MedChemComm 10(9): 1599.
- Galles, Celina, Prez, Gastón M., Penkov, Sider, Boland, Sebastian, Porta, Exequiel O. J., Altabe, Silvia G., Labadie, Guillermo R., Schmidt, Ulrike, Knölker, Hans-Joachim, Kurzchalia, Teymuras V. & de Mendoza, Diego (2018). Endocannabinoids in Caenorhabditis elegans are essential for the mobilization of cholesterol from internal reserves. Scientific Reports 8(1).
- Panozzo-Zénere, Esteban A., Porta, Exequiel O.J., Arrizabalaga, Gustavo, Fargnoli, Lucía, Khan, Shabana I., Tekwani, Babu L. & Labadie, Guillermo R. (2018). A minimalistic approach to develop new anti-apicomplexa polyamines analogs. European Journal of Medicinal Chemistry 143: 866.
- Porta, Exequiel O. J., Vallejos, Margarita M., Bracca, Andrea B. J. & Labadie, Guillermo R. (2017). Experimental and theoretical studies of the [3,3]-sigmatropic rearrangement of prenyl azides. RSC Adv 7(75): 47527.
- Porta, Exequiel O. J., Jäger, Sebastián N., Nocito, Isabel, Lepesheva, Galina I., Serra, Esteban C., Tekwani, Babu L. & Labadie, Guillermo R. (2017). Antitrypanosomal and antileishmanial activity of prenyl-1,2,3-triazoles. MedChemComm 8(5): 1015.
- Jäger, Sebastián N., Porta, Exequiel O. J. & Labadie, Guillermo R. (2016). Tuning the Lewis acid phenol ortho-prenylation as a molecular diversity tool. Molecular Diversity 20(2): 407.
- Sussmann, Rodrigo A.C., de Moraes, Marcilio M., Cebrián-Torrejón, Gerardo, Porta, Exequiel O., Doménech-Carbó, Antonio, Yamaguchi, Lydia F., Katzin, Alejandro M. & Kato, Massuo J. (2016). Stabilization and detection of hydrophylloquinone as di- O -methyl derivative. Journal of Chromatography B 1033-1034: 368.
- Porta, Exequiel O.J., Carvalho, Paulo B., Avery, Mitchell A., Tekwani, Babu L. & Labadie, Guillermo R. (2014). Click chemistry decoration of amino sterols as promising strategy to developed new leishmanicidal drugs. Steroids 79: 28.