Staff profile

Journal Article

• Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence
  
  Went, S. C., Picton, D. M., Morgan, R. D., Nelson, A., Brady, A., Mariano, G., Dryden, D. T. F., Smith, D. L., Wenner, N., Hinton, J. C. D., & Blower, T. R. (2024). Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence. Nature Communications, 15, Article 7236. https://doi.org/10.1038/s41467-024-51629-7
• Phage anti-CRISPR control by an RNA- and DNA-binding helix–turn–helix protein
  
  Birkholz, N., Kamata, K., Feussner, M., Wilkinson, M. E., Cuba Samaniego, C., Migur, A., Kimanius, D., Ceelen, M., Went, S. C., Usher, B., Blower, T. R., Brown, C. M., Beisel, C. L., Weinberg, Z., Fagerlund, R. D., Jackson, S. A., & Fineran, P. C. (2024). Phage anti-CRISPR control by an RNA- and DNA-binding helix–turn–helix protein. Nature, 631(8021), 670-677. https://doi.org/10.1038/s41586-024-07644-1
• Multi-layered genome defences in bacteria
  
  Agapov, A., Baker, K., Bedekar, P., Bhatia, R., Blower, T. R., Brockhurst, M. A., Brown, C., Chong, C., Fothergill, J. L., Graham, S., Hall, J. P. J., Maestri, A., McQuarrie, S., Olina, A., Pagliara, S., Recker, M., Richmond, A., Shaw, S. J., Szczelkun, M. D., … Wright, R. (2024). Multi-layered genome defences in bacteria. Current Opinion in Microbiology, 78, Article 102436. https://doi.org/10.1016/j.mib.2024.102436
• Diverse Durham collection phages demonstrate complex BREX defence responses
  
  Kelly, A., Went, S. C., Mariano, G., Shaw, L. P., Picton, D. M., Duffner, S. J., Coates, I., Herdman-Grant, R., Gordeeva, J., Drobiazko, A., Isaev, A., Lee, Y.-J., Luyten, Y., Morgan, R. D., Weigele, P., Severinov, K., Wenner, N., Hinton, J. C., & Blower, T. R. (2023). Diverse Durham collection phages demonstrate complex BREX defence responses. Applied and Environmental Microbiology, 89(9), Article e00623-23. https://doi.org/10.1128/aem.00623-23