Staff profile

Journal Article

• Photoactivated cell-killing involving a low molecular weight, donor-acceptor diphenylacetylene
  
  Chisholm, D., Lamb, R., Pallett, T., Affleck, V., Holden, C., Marrison, J., O’Toole, P., Ashton, P., Newling, K., Steffen, A., Nelson, A., Mahler, C., Valentine, R., Blacker, T., Bain, A. J., Girkin, J. M., Marder, T. B., Whiting, A., & Ambler, C. A. (2019). Photoactivated cell-killing involving a low molecular weight, donor-acceptor diphenylacetylene. Chemical Science, 10(17), 4673-4683. https://doi.org/10.1039/c9sc00199a
• Fluorescent retinoic acid analogues as probes for biochemical and intracellular characterization of retinoid signalling pathways
  
  Chisholm, D., Tomlinson, C., Zhou, G.-L., Holden, C., Affleck, V., Lamb, R., Newling, K., Ashton, P., Valentine, R., Redfern, C., Erostyak, J., Makkai, G., Ambler, C., Whiting, A., & Pohl, E. (2019). Fluorescent retinoic acid analogues as probes for biochemical and intracellular characterization of retinoid signalling pathways. ACS Chemical Biology, 14(3), 369-377. https://doi.org/10.1021/acschembio.8b00916
• Manufacture of Third-Generation Lentivirus for Preclinical Use, with Process Development Considerations for Translation to Good Manufacturing Practice
  
  Gándara, C., Affleck, V., & Stoll, E. A. (2018). Manufacture of Third-Generation Lentivirus for Preclinical Use, with Process Development Considerations for Translation to Good Manufacturing Practice. Human Gene Therapy Methods, 29(1). https://doi.org/10.1089/hgtb.2017.098
• Fatty acid oxidation is required for the respiration and proliferation of malignant glioma cells
  
  Lin, H., Patel, S., Affleck, V. S., Wilson, I., Turnbull, D. M., Joshi, A. R., Maxwell, R., & Stoll, E. A. (2017). Fatty acid oxidation is required for the respiration and proliferation of malignant glioma cells. Neuro-Oncology, 19(1), 43-54. https://doi.org/10.1093/neuonc/now128
• The projection and synaptic organisation of NTS afferent connections with presympathetic neurones, GABA and nNOS neurons in the paraventricular nucleus of the hypothalamus
  
  Affleck, V., Coote, J., & Pyner, S. (2012). The projection and synaptic organisation of NTS afferent connections with presympathetic neurones, GABA and nNOS neurons in the paraventricular nucleus of the hypothalamus. Neuroscience, 219, 48-61. https://doi.org/10.1016/j.neuroscience.2012.05.070
• Proof of function of a putative 3-hydroxyacyl-acyl carrier protein dehydratase from higher plants by mass spectrometry of product formation.
  
  Brown, A., Affleck, V., Kroon, J., & Slabas, A. (2009). Proof of function of a putative 3-hydroxyacyl-acyl carrier protein dehydratase from higher plants by mass spectrometry of product formation. FEBS Letters, 583(2), 363-368. https://doi.org/10.1016/j.febslet.2008.12.022
• Tandem affinity purification tagging of fatty acid biosynthetic enzymesin Synechocystis sp PCC6803 and Arabidopsis thaliana
  
  Brown, A. P., Affleck, V., Fawcett, T., & Slabas, A. R. (2006). Tandem affinity purification tagging of fatty acid biosynthetic enzymesin Synechocystis sp PCC6803 and Arabidopsis thaliana. Journal of Experimental Botany, 57(7), 1563-1571. https://doi.org/10.1093/jxb/erj150