Staff profile

• cell adhesion
• cellular and molecular biology of epithelial tissues
• function of the cytoskeleton
• regulation of gene expression
• skin biology

Chapter in book

• Boczonadi, V., & Määttä, A. (2016). Functional Analysis of Periplakin and Envoplakin, Cytoskeletal Linkers, and Cornified Envelope Precursor Proteins. In K. Wilson, & A. Sonnenberg (Eds.), Intermediate Filament Associated Proteins (309-329). Elsevier. https://doi.org/10.1016/bs.mie.2015.06.019
• Maatta, A., Hutchison, C. J., & Watson, M. (2004). Spectraplakins and nesprins, giant spectrin repeat proteins participating in the organization of the cytoskeleton and the nuclear envelope. In D. Evans, C. Hutchison, & J. Bryant (Eds.), The Nuclear Envelope (265-277). BIOS/Garland Science

Journal Article

• Tan, C. Y. R., Morenc, M., Setiawan, M., Lim, Z. Z. Y., Soon, A. L., Bierman, J. C., Vires, L., Laughlin, T., DeAngelis, Y. M., Rovito, H., Jarrold, B. B., Nguyen, T. Q. N., Lim, J. S. Y., Kent, O., Määttä, A., Benham, A. M., Hawkins, T. J., Lee, X. E., Ehrman, M. C., Oblong, J. E., …Bellanger, S. (2024). Para-Hydroxycinnamic Acid Mitigates Senescence and Inflammaging in Human Skin Models. International Journal of Molecular Sciences, 25(15), Article 8153. https://doi.org/10.3390/ijms25158153
• Costello, L., Goncalves, K., De Los Santos Gomez, P., Simpson, A., Maltman, V., Ritchie, P., Tasseff, R., Isfort, R., Dicolandrea, T., Wei, X., Määttä, A., Karakesisoglou, I., Markiewicz, E., Bascom, C. C., & Przyborski, S. (2023). Quantitative morphometric analysis of intrinsic and extrinsic skin ageing in individuals with Fitzpatrick skin types II–III. Experimental Dermatology, 32(5), 620-631. https://doi.org/10.1111/exd.14754
• Määttä, A., Nixon, R., Robinson, N., Ambler, C. A., Goncalves, K., Maltman, V., & Przyborski, S. (2023). Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23. Journal of Cosmetic Dermatology, 22(5), https://doi.org/10.1111/jocd.15629
• Johnson, S., Cowley, K., Hawkins, T. J., & Määttä, A. (2019). Pulling force deforms hair follicle root sheath nuclei and surrounding dermal collagen matrix differently at infundibulum, isthmus and suprabulbar regions. Experimental Dermatology, 28(7), 862-866. https://doi.org/10.1111/exd.13948
• Roger, M., Fullard, N., Costello, L., Bradbury, S., Markiewicz, E., O'Reilly, S., Darling, N., Ritchie, P., Määttä, A., Karakesisoglou, I., Nelson, G., von Zglinicki, T., Dicolandrea, T., Isfort, R., Bascom, C., & Przyborski, S. (2019). Bioengineering the Microanatomy of Human Skin. Journal of Anatomy, 234(4), 438-455. https://doi.org/10.1111/joa.12942
• Duit, R., Hawkins, T. J., & Määttä, A. (2019). Depilatory chemical thioglycolate affects hair cuticle and cortex, degrades epidermal cornified envelopes and induces proliferation and differentiation responses in keratinocytes. Experimental Dermatology, 28(1), 76-79. https://doi.org/10.1111/exd.13838
• Maruthappu, T., McGinty, L. A., Blaydon, D. C., Fell, B., Määttä, A., Duit, R., Hawkins, T., Braun, K. M., Simpson, M. A., O’Toole, E. A., & Kelsell, D. P. (2018). Recessive Mutation in FAM83G Associated with Palmoplantar Keratoderma and Exuberant Scalp Hair. Journal of Investigative Dermatology, 138(4), 984-987. https://doi.org/10.1016/j.jid.2017.10.031
• Marsh, J., Whitaker, S., Felts, T., Shearouse, W., Vatter, M., Määttä, A., Thompson, M., & Hawkins, T. (2018). Role of internal lipids in hair health
• Boczonadi, V., & Määttä, A. (2012). Annexin A9 is a periplakin interacting partner in membrane-targeted cytoskeletal linker protein complexes. FEBS Letters, 586(19), 3090-3096. https://doi.org/10.1016/j.febslet.2012.07.057
• McInroy, L., & Maatta, A. (2011). Plectin regulates invasiveness of SW480 colon carcinoma cells and is targeted to podosome-like adhesions in an isoform-specific manner. Experimental Cell Research, 317(17), 2468-2478. https://doi.org/10.1016/j.yexcr.2011.07.013
• Richardson, G., Fantauzzo, K., Bazzi, H., Määttä, A., & Colin, J. (2009). Dynamic expression of Syndecan-1 during hair follicle morphogenesis. Gene Expression Patterns, 9(6), 454-460. https://doi.org/10.1016/j.gep.2009.04.004
• Ambler, C., & Maatta, A. (2009). Epidermal stem cells: location, potential and contribution to cancer. Journal of Pathology, 217, https://doi.org/10.1002/path.2468
• Ojeh, N., Pekovic, V., Jahoda, C., & Maatta, A. (2008). The MAGUK-family protein CASK is targeted to nuclei of the basal epidermis and controls keratinocyte proliferation. Journal of Cell Science, 121(16), 2705-2717. https://doi.org/10.1242/jcs.025643
• Sevilla, L., Nachat, R., Groot, K., Klement, J., Uitto, J., Djian, P., Määttä, A., & Watt, F. (2007). Mice deficient in involucrin, envoplakin and periplakin have a defective epidermal barrier. Journal of Cell Biology, 179(7), 1599-1612. https://doi.org/10.1083/jcb.200706187
• Boczonadi, V., McInroy, L., & Maatta, A. (2007). Cytolinker Cross-talk: Periplakin N-terminus Interacts with Plectin to Regulate Keratin Organisation and Epithelial Migration. Experimental Cell Research, 313(16), 3579-3591. https://doi.org/10.1016/j.yexcr.2007.07.005
• McInroy, L., & Maatta, A. (2007). Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion. Biochemical and Biophysical Research Communications, 360(1), 109-114. https://doi.org/10.1016/j.bbrc.2007.06.036
• Ojeh, N., Hiilesvuo, K., Wärri, A., Salmivirta, M., Henttinen, T., & Maatta, A. (2007). Ectopic expression of syndecan-1 in basal epidermis affects keratinocyte proliferation and wound re-epithelialization. Journal of Investigative Dermatology, 128(1), 26-34. https://doi.org/10.1038/sj.jid.5700967
• Long, H. A., Boczonadi, V., McInroy, L., Goldberg, M., & Maatta, A. (2006). Periplakin-dependent re-organisation of keratin cytoskeleton and loss of collective migration in Keratin 8 down-regulated epithelial sheets. Journal of Cell Science, 119(24), 5147-5159. https://doi.org/10.1242/jcs.03304
• Maatta, A. (2004). Roads to the edge of the cell – Intracellular transport of cornified envelope precursors. Journal of Investigative Dermatology, 122(1), xii-xiii
• Maatta, A., Di Colandrea, T., Groot, K., & Watt Fiona, M. (2001). Gene targeting of envoplakin, a cytoskeletal linker protein and precursor of epidermal cornified envelope. Molecular and Cellular Biology, 21(20), 7047-7053. https://doi.org/10.1128/mcb.21.20.7047-7053.2001
• DiColandrea, T., Karashima, T., Maatta, A., & Watt, F. M. (2000). Subcellular distribution of envoplakin and periplakin: insights into their role as precursors of the epidermal cornified envelope. Journal of Cell Biology, 151, 573-586. https://doi.org/10.1083/jcb.151.3.573
• Maatta, A., Ruhrberg, C., & Watt, F. M. (2000). Structure and regulation of the envoplakin gene. Journal of Biological Chemistry, 275(26), 19857-19865. https://doi.org/10.1074/jbc.m001028200

Working Paper

• Kent, O., Casey, E. R., Brown, M., Bell, S., Ehrman, M., Flagler, M., Määttä, A., Benham, A. M., & Hawkins, T. J. (2024). New imaging tools reveal live cellular collagen secretion, fibril dynamics and network organisation