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Professor Ashraf William Khir


PGCert, BSc, MSc, PhD

AffiliationRoom numberTelephone
Professor in the Department of EngineeringE107 Christopherson 


Ashraf W Khir has carried out his PhD work (1996-2000) with Prof Kim H Parker in the Deartment of Bioengineering at Imperial College London and his Thesis dealt with the effect of aortic occlusion on the hemodynamics in the ascending aorta and left ventricular performance. The In Vivo experiments were carried out in the late Prof John V Tyberg's laboratory at Calgary Medical Centre and the Human data were collected at the Derek Gibson Echocardiography Department at the Royal Brompton Hospital. Ashraf then carried a 3 years (2000-2003) postdoctoral fellowship at the National Heart and Lung Institute (NHLI), with Prof John R Pepper, studying the mechanics of the Intra aortic Balloon Pump (IABP).

Ashraf then obtained his first tenure post as a lecturer at Brunel University London in 2003, and remained there for 18 years, during which he was promoted to Chair in Cardiovascular Mechanics in 2016 and was the Biomedical Engineering Theme Leader. In January 2022, Ashraf moved to Durham University as the Bioengineering Node Leader and his research is generally in the area of arterial and cardiac (cardiovascular) mechanics.

Research interests

  • I work broadly in the fields of cardiovascular mechanics, with particular interest in the physiological fluid mechanics and ventricular assist devices (VADs). My academic research is linked to two clinical pathologies: hypertension and heart failure.
  • I have special interest in the following topics:
  • - Noninvasive determination of hemodynamic parameters
  • - In vitro testing and mock circulatory loops
  • - Characterisation of wave reflections
  • - Rotary and pulsatile blood pumps
  • - Estimation of arterial wave speed
  • - Intra Aortic balloon pump (IABP)
  • - Arterial wave propagation
  • - Arterial wall mechanics
  • - Wave intensity analysis
  • - Air flow in lungs

Esteem Indicators

  • 0000: Board membership: Governing board member of the European Society for Artificial Organs (ESAO, 2010 – 2016)
  • 0000: Editorship:: 1) Associate Editor, Journal of Engineering in Medicine (2019 - todate)

    2) Co-Editor ‘Artificial Organs’ Journal (2013 – to date).

  • 0000: External Examiner: External Examiner MSc Biomedical Engineering, City University (2015 – 2019)
  • 0000: Fellowship: Fellow FIPEM (2016 to date)

    Fellow IMechE (2018 - to date)


Conference Paper

Journal Article

Supervision students