Staff profile

I work on seaweed, primarily on their evolution and systematics, but also on their bioenergy potential and their ecological importance along the UK’s coastlines. 

My DPhil in Biochemistry was awarded in 2000 and between 2000-2007 I held postdoctoral research fellowships in Cambridge, Plymouth and Roscoff, taking a year off in 2002-2003 to play professional rugby. From 2009-2012, I held a Lectureship at Queen’s University Belfast and moved to Durham in 2013.

• Seaweed systematics and evolution
• The genetics, genomics and physiology of algal development
• Bioenergy generation and provision

• Durham Centre for Crop Improvement Technology
• Ecology, Evolution & Environment
• Energy Policy Group
• Molecular Plant Sciences

Journal Article

• Wylot, Marta, Whittaker, David T.E., Wren, Stephen A.C., Bothwell, John H., Hughes, Leslie & Griffin, Julian L. (2021). Monitoring apoptosis in intact cells by high‐resolution magic angle spinning 1 H NMR spectroscopy. NMR in Biomedicine 34(3): e4456.
• De Clerck, Olivier Kao, Shu-Min Bogaert, Kenny A. Blomme, Jonas Foflonker, Fatima Kwantes, Michiel Vancaester, Emmelien Vanderstraeten, Lisa Aydogdu, Eylem Boesger, Jens Califano, Gianmaria Charrier, Benedicte Clewes, Rachel Del Cortona, Andrea D’Hondt, Sofie Fernandez-Pozo, Noe Gachon, Claire M. Hanikenne, Marc Lattermann, Linda Leliaert, Frederik Liu, Xiaojie Maggs, Christine A. Popper, Zoë A. Raven, John A. Van Bel, Michiel Wilhelmsson, Per K.I. Bhattacharya, Debashish Coates, Juliet C. Rensing, Stefan A. Van Der Straeten, Dominique Vardi, Assaf Sterck, Lieven Vandepoele, Klaas Van de Peer, Yves Wichard, Thomas & Bothwell, John H. (2018). Insights into the Evolution of Multicellularity from the Sea Lettuce Genome. Current Biology 28(18): 2921-2933.e5.
• Ramessur, Anusha Devi, Bothwell, John H., Maggs, Christine A., Gan, Sook Yee & Phang, Siew Moi (2018). Agrobacterium-mediated gene delivery and transient expression in the red macroalga Chondrus crispus. Botanica Marina 61(5): 499-510.
• Reddin, Carl J., Bothwell, John H., O'Connor, Nessa E. & Harrod, Chris (2018). The effects of spatial scale and isoscape on consumer isotopic niche width. Functional Ecology 32(4): 904-915.
• Trivedi, Nitin, Baghel, Ravi S., Bothwell, John, Gupta, Vishal, Reddy, C.R.K., Lali, Arvind M. & Jha, Bhavanath (2016). An integrated process for the extraction of fuel and chemicals from marine macroalgal biomass. Scientific Reports 6(1): 30728.
• Reddin, C.J., Bothwell, J.H. & Lennon, J.J. (2015). Between-taxon matching of common and rare species richness patterns. Global Ecology and Biogeography 24(12): 1476-1486.
• Reddin, C.J., Docmac, F., O’Connor, N.E., Bothwell, J.H. & Harrod, C. (2015). Coastal Upwelling Drives Intertidal Assemblage Structure and Trophic Ecology. PLoS ONE 10(7): e0130789.
• Wichard, T., Charrier, B., Mineur, B., Bothwell, J.H., De Clerck, O. & Coates, J.C. (2015). The green seaweed Ulva: a model system to study morphogenesis. Frontiers in Plant Science 6: 72.
• Ahmed, S., Cock, J.M., Pessia, E., Luthringer, R., Cormier, A., Robuchon, M., Sterck, L., Peters, A.F., Dittami, S.M., Corre, E., Valero, M., Aury, J.M., Roze, D., Van de Peer, Y., Bothwell, J., Marais, G.A. & Coelho, S.M. (2014). A haploid system of sex determination in the brown alga Ectocarpus sp. Current Biology 24(17): 1945-1957.
• Collén, Jonas, Porcel, Betina, Carré, Wilfrid, Ball, Steven G., Chaparro, Cristian, Tonon, Thierry, Barbeyron, Tristan, Michel, Gurvan, Noel, Benjamin, Valentin, Klaus, Elias, Marek, Artiguenave, François, Arun, Alok, Aury, Jean-Marc, Barbosa-Neto, José F., Bothwell, John H., Bouget, François-Yves, Brillet, Loraine, Cabello-Hurtado, Francisco, Capella-Gutiérrez, Salvador, Charrier, Bénédicte, Cladière, Lionel, Cock, J. Mark, Coelho, Susana M., Colleoni, Christophe, Czjzek, Mirjam, Da Silva, Corinne, Delage, Ludovic, Denoeud, France, Deschamps, Philippe, Dittami, Simon M., Gabaldón, Toni, Gachon, Claire M. M., Groisillier, Agnès, Hervé, Cécile, Jabbari, Kamel, Katinka, Michael, Kloareg, Bernard, Kowalczyk, Nathalie, Labadie, Karine, Leblanc, Catherine, Lopez, Pascal J., McLachlan, Deirdre H., Meslet-Cladiereb, Laurence, Moustafa, Ahmed, Nehr, Zofia, Collén, Pi Nyvall, Panaud, Olivier, Partensky, Frédéric, Poulain, Julie, Rensing, Stefan A., Rousvoal, Sylvie, Samson, Gaelle, Symeonidi, Aikaterini, Weissenbach, Jean, Zambounis, Antonios, Wincker, Patrick & Boyen, Catherine (2013). Genome structure and metabolic features in the red seaweed Chondrus crispus shed light on evolution in the Archaeplastida. Proceedings of the National Academy of Sciences 110(13): 5247-5252.
• Anderson, Alexander, Bothwell, John H., Laohavisit, Anuphon, Smith, Alison G. & Davies, Julia M. (2011). NOX or not? Evidence for algal NADPH oxidases. TRENDS IN PLANT SCIENCE 16(11): 579-581.
• Bothwell, John H. F. & Griffin, Julian L. (2011). An introduction to biological nuclear magnetic resonance spectroscopy. Biological Reviews 86(2): 493-510.
• Cock, J. Mark, Sterck, Lieven, Rouze, Pierre, Scornet, Delphine, Allen, Andrew E., Amoutzias, Grigoris, Anthouard, Veronique, Artiguenave, Francois, Aury, Jean-Marc, Badger, Jonathan H., Beszteri, Bank, Billiau, Kenny, Bonnet, Eric, Bothwell, John H., Bowler, Chris, Boyen, Catherine, Brownlee, Colin, Carrano, Carl J., Charrier, Benedicte, Cho, Ga Youn, Coelho, Susana M., Collen, Jonas, Corre, Erwan, Da Silva, Corinne, Delage, Ludovic, Delaroque, Nicolas, Dittami, Simon M., Doulbeau, Sylvie, Elias, Marek, Farnham, Garry, Gachon, Claire M. M., Gschloessl, Bernhard, Heesch, Svenja, Jabbari, Kamel, Jubin, Claire, Kawai, Hiroshi, Kimura, Kei, Kloareg, Bernard, Kuepper, Frithjof C., Lang, Daniel, Le Bail, Aude, Leblanc, Catherine, Lerouge, Patrice, Lohr, Martin, Lopez, Pascal J., Martens, Cindy, Maumus, Florian, Michel, Gurvan, Miranda-Saavedra, Diego, Morales, Julia, Moreau, Herve, Motomura, Taizo, Nagasato, Chikako, Napoli, Carolyn A., Nelson, David R., Nyvall-Collen, Pi, Peters, Akira F., Pommier, Cyril, Potin, Philippe, Poulain, Julie, Quesneville, Hadi, Read, Betsy, Rensing, Stefan A., Ritter, Andres, Rousvoal, Sylvie, Samanta, Manoj, Samson, Gaelle, Schroeder, Declan C., Segurens, Beatrice, Strittmatter, Martina, Tonon, Thierry, Tregear, James W., Valentin, Klaus, von Dassow, Peter, Yamagishi, Takahiro, Van de Peer, Yves & Wincker, Patrick (2010). The Ectocarpus genome and the independent evolution of multicellularity in brown algae. NATURE 465(7298): 617-621.
• Bothwell, J.H., Marie, D., Peters, A.F., Cock, J.M. & Coelho, S.M.B. (2010). Role of endoreduplication and apomeiosis during parthenogenetic reproduction in the model brown alga Ectocarpus siliculosus. New Phytologist 188(1): 111-121.
• Miedema, H., Demidchik, V., Véry, A.A., Bothwell, J.H., Brownlee, C. & Davies, J.M. (2008). Two voltage-dependent calcium channels co-exist in the apical plasma membrane of Arabidopsis thaliana root hairs. New Phytologist 179(2): 378–385.
• Coelho, S.M.B., Brownlee, C. & Bothwell, J.H.F. (2008). A tip-high, Ca2+-interdependent, reactive oxygen species gradient is associated with polarized growth in Fucus serratus zygotes. Planta 227(5): 1037-1046.
• Bothwell, J.H., Kisielewska, J., Genner, M.J., McAinsh, M.R. & Brownlee, C. (2008). Ca2+ signals co-ordinate zygotic polarization and cell cycle progression in the brown alga, Fucus serratus. Development 135(12): 2173-2181.
• Bothwell, JHF (2006). The long past of systems biology. NEW PHYTOLOGIST 170(1): 6-10.
• Bothwell, JHF, Brownlee, C, Hetherington, AM, Ng, CKY, Wheeler, GL & McAinsh, MR (2006). Biolistic delivery of Ca2+ dyes into plant and algal cells. PLANT JOURNAL 46(2): 327-335.
• Bothwell, JHF & Ng, CKY (2005). The evolution of Ca2+ signalling in photosynthetic eukaryotes. NEW PHYTOLOGIST 166(1): 21-38.
• Foreman, J, Demidchik, V, Bothwell, JHF, Mylona, P, Miedema, H, Torres, MA, Linstead, P, Costa, S, Brownlee, C, Jones, JDG, Davies, JM & Dolan, L (2003). Reactive oxygen species produced by NADPH oxidase regulate plant cell growth. NATURE 422(6930): 442-446.
• Rae, C, Griffin, JL, Blair, DH, Bothwell, JH, Bubb, WA, Maitland, A & Head, S (2002). Abnormalities in brain biochemistry associated with lack of dystrophin: studies of the mdx mouse. NEUROMUSCULAR DISORDERS 12(2): 121-129.
• Bothwell, JH, Styles, P & Bhakoo, KK (2002). Swelling-activated taurine and creatine effluxes from rat cortical astrocytes are pharmacologically distinct. JOURNAL OF MEMBRANE BIOLOGY 185(2): 157-164.
• Bothwell, JH, Rae, C, Dixon, RM, Styles, P & Bhakoo, KK (2001). Hypo-osmotic swelling-activated release of organic osmolytes in brain slices: implications for brain oedema in vivo. JOURNAL OF NEUROCHEMISTRY 77(6): 1632-1640.
• Miedema, H, Bothwell, JHF, Brownlee, C & Davies, JM (2001). Calcium uptake by plant cells - channels and pumps acting in concert. TRENDS IN PLANT SCIENCE 6(11): 514-519.
• Hanke, GT, Northrop, FD, Devine, GR, Bothwell, JHF & Davies, JM (2001). Chloride channel antagonists perturb growth and morphology of Neurospora crassa. FEMS MICROBIOLOGY LETTERS 201(2): 243-247.