Staff profile
Overview
Dr Matthew Kitching
Royal Society University Research Fellow and Associate Professor
Affiliation | Telephone |
---|---|
Royal Society University Research Fellow and Associate Professor in the Department of Chemistry | +44 (0) 191 33 42127 |
Fellow of the Wolfson Research Institute for Health and Wellbeing | +44 (0) 191 33 42127 |
Biography
Kitching Group Summary
Image of walker adapted from John Lieber's image at https://www.artofthecell.com/
Research interests
- Synthetic Chemistry
- Supramolecular Chemistry & Functional Molecules
- Chemical Patterning, Soft Materials, and Interfaces
Publications
Journal Article
- Walsh, M. P., Barclay, J. A., Begg, C. S., Xuan, J., & Kitching, M. O. (2023). Conglomerate Crystallization in the Cambridge Structural Database (2020–2021). Crystal Growth and Design, 23(4), 2837-2837. https://doi.org/10.1021/acs.cgd.3c00019
- Walsh, M. P., Barclay, J. A., Begg, C. S., Xuan, J., Johnson, N. T., Cole, J. C., & Kitching, M. O. (2022). Identifying a Hidden Conglomerate Chiral Pool in the CSD. JACS Au, 2(10), 2235-2250. https://doi.org/10.1021/jacsau.2c00394
- Snieckus, V., Patel, J., Kitching, M., Dalziel, M., Cosman, J., & Kaye, M. (2019). Regioselective Functionalization of 7‐Azaindole by Controlled Annular Isomerism: The Directed Metalation‐Group Dance. Angewandte Chemie, 131(22), 7391-7395. https://doi.org/10.1002/ange.201901724
- Snieckus, V., Kitching, M., Laars, M., Board, J., Patel, J., & Gan, W. (2018). Directed Remote Lateral Metalation: Highly Substituted 2-Naphthols and BINOLs by in situ Directing Group Generation. Angewandte Chemie, 130(30), 9569-9573. https://doi.org/10.1002/ange.201805203
- Patel, J. J., Laars, M., Gan, W., Board, J., Kitching, M. O., & Snieckus, V. (2018). Directed Remote Lateral Metalation: Highly Substituted 2-Naphthols and BINOLs by In Situ Generation of a Directing Group. Angewandte Chemie International Edition, 57(30), 9425-9429. https://doi.org/10.1002/anie.201805203
- Kitching, M. O., Dixon, O. E., Baumann, M., & Baxendale, I. R. (2017). Flow-Assisted Synthesis: A Key Fragment of SR 142948A. European Journal of Organic Chemistry, 2017(44), 6540-6553. https://doi.org/10.1002/ejoc.201700904
- De Bo, G., Gall, M. A., Kitching, M. O., Kuschel, S., Leigh, D. A., Tetlow, D. J., & Ward, J. W. (2017). Sequence-Specific β-Peptide Synthesis by a Rotaxane-Based Molecular Machine. Journal of the American Chemical Society, 139(31), 10875-10879. https://doi.org/10.1021/jacs.7b05850
- Gil-Ramirez, G., Hoekman, S., Kitching, M. O., Leigh, D. A., Vitorica-Yrezabal, I. J., & Zhang, G. (2016). Tying a Molecular Overhand Knot of Single Handedness and Asymmetric Catalysis with the Corresponding Pseudo-D-3-Symmetric Trefoil Knot. Journal of the American Chemical Society, 138(40), 13159-13162. https://doi.org/10.1021/jacs.6b08421
- Hurst, T. E., Kitching, M. O., da Frota, L. C., Guimaraes, K. G., Dalziel, M. E., & Snieckus, V. (2015). Metal-Free Synthesis of Dibenzoxazepinones via a One-Pot SNAr and Smiles Rearrangement Process: Orthogonality with Copper-Catalyzed Cyclizations. Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry, 26(11), 1455-1460. https://doi.org/10.1055/s-0034-1378839
- Hoekman, S., Kitching, M. O., Leigh, D. A., Papmeyer, M., & Roke, D. (2015). Goldberg Active Template Synthesis of a [2]Rotaxane Ligand for Asymmetric Transition-Metal Catalysis. Journal of the American Chemical Society, 137(24), 7656-7659. https://doi.org/10.1021/jacs.5b04726
- Baxendale, I., Cheung, S., Kitching, M., Ley, S., & Shearman, J. (2013). The synthesis of neurotensin antagonist SR 48692 for prostate cancer research. Bioorganic and Medicinal Chemistry, 21(14), 4378-4387. https://doi.org/10.1016/j.bmc.2013.04.075
- Battilocchio, C., Deadman, B. J., Nikbin, N., Kitching, M. O., Baxendale, I. R., & Ley, S. V. (2013). A Machine-Assisted Flow Synthesis of SR48692: A Probe for the Investigation of Neurotensin Receptor-1. Chemistry - A European Journal, 19(24), 7917-7930. https://doi.org/10.1002/chem.201300696
- Battilocchio, C., Baxendale, I. R., Biava, M., Kitching, M. O., & Ley, S. V. (2012). A Flow-Based Synthesis of 2-Aminoadamantane-2-carboxylic Acid. Organic Process Research and Development, 16(5), 798-810. https://doi.org/10.1021/op300084z
- Battilocchio, C., Baumann, M., Baxendale, I. R., Biava, M., Kitching, M. O., Ley, S. V., Martin, R. E., Ohnmacht, S. A., & Tappin, N. D. (2012). Scale-Up of Flow-Assisted Synthesis of C-2-Symmetric Chiral PyBox Ligands. Synthesis: Journal of Synthetic Organic Chemistry, 44(4), 635-647. https://doi.org/10.1055/s-0031-1289676
- Kitching, M. O., & Snieckus, V. (2012). Organic chemistry - Directors extend their reach. Nature, 486(7404), 478-479. https://doi.org/10.1038/486478a
- Kitching, M. O., Hurst, T. E., & Snieckus, V. (2012). Copper-Catalyzed Cross-Coupling Interrupted by an Opportunistic Smiles Rearrangement: An Efficient Domino Approach to Dibenzoxazepinones. Angewandte Chemie International Edition, 51(12), 2925-2929. https://doi.org/10.1002/anie.201106786
- Seechurn, C. C. J., Kitching, M. O., Colacot, T. J., & Snieckus, V. (2012). Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize. Angewandte Chemie International Edition, 51(21), 5062-5085. https://doi.org/10.1002/anie.201107017
- Tozzi, F., Ley, S. V., Kitching, M. O., & Baxendale, I. R. (2010). Enzymatic Oxidative Cyclisation Reactions Leading to Dibenzoazocanes. Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry, 2010(13), 1919-1922. https://doi.org/10.1055/s-0030-1258486
- Myers, R. M., Shearman, J. W., Kitching, M. O., Ramos-Montoya, A., Neal, D. E., & Ley, S. V. (2009). Cancer, Chemistry, and the Cell: Molecules that Interact with the Neurotensin Receptors. ACS Chemical Biology, 4(7), 503-525. https://doi.org/10.1021/cb900038e
- Aureggi, V., Franckevičius, V., Kitching, M., Ley, S., Longbottom, D., Oelke, A., & Sedelmeier, G. (2008). (S)-5-PYRROLIDIN-2-YL-1H-TETRAZOLE. Organic syntheses, 85(72), https://doi.org/10.15227/orgsyn.085.0072
- Baumann, M., Baxendale, I. R., Hayward, J. J., Hopkin, M. D., Jin, J., Kitching, M. O., Lanners, S., Ley, S. V., Nikbin-Roudsari, N., Smith, C. D., Smith, C. J., & Tamborini, L. (2008). New opportunities for advanced organic synthesis-flow-based chemical processing
Supervision students
Alexander Lee
Corey Stewart
Research Postgraduate
Diego Alvarez Bustos
Research Postgraduate
Emanuella Fiandra
Research Postgraduate
Haijing Wang
Research Postgraduate
Haoyang Wang
Jamie Hunter
Research Postgraduate
Jinyi Xuan
Research Postgraduate
Ross Young
Yingfeng Zhang
Research Postgraduate
Yuzhen Wen
Research Postgraduate