Staff profile

• Biomolecular Interactions

Journal Article

• Thompson, H.L., Shen, W., Matus, R., Kakkar, M., Jones, C., Dolan, D., Grellscheid, S., Yang, X., Zhang, N., Mozaffari-Jovin, S., Chen, C., Zhang, X., Topping, J.F. & Lindsey, K. (2023). MERISTEM-DEFECTIVE regulates the balance between stemness and differentiation in the root meristem through RNA splicing control. Development 150(7): dev201476.
• Abbas, Manzar, Law, Jack O., Grellscheid, Sushma N., Huck, Wilhelm T. S. & Spruijt, Evan (2022). Peptide‐Based Coacervate‐Core Vesicles with Semipermeable Membranes. Advanced Materials 34(34): 2202913.
• O’Hare, Ciaran A. J., Matsos, Vassili G., Newton, Joseph, Smith, Karl, Hochstetter, Joel, Jaiswar, Ravi, Kyaw, Wunna, McNamara, Aimee, Kuncic, Zdenka, Grellscheid, Sushma Nagaraja & Bœhm, Céline (2022). Particle detection and tracking with DNA. The European Physical Journal C 82(4): 306.
• Chyżyńska, Katarzyna, Labun, Kornel, Jones, Carl, Grellscheid, Sushma N & Valen, Eivind (2021). Deep conservation of ribosome stall sites across RNA processing genes. NAR Genomics and Bioinformatics 3(2).
• Lagnado, Anthony, Leslie, Jack, Ruchaud‐Sparagano, Marie‐Helene, Victorelli, Stella, Hirsova, Petra, Ogrodnik, Mikolaj, Collins, Amy L, Vizioli, Maria Grazia, Habiballa, Leena, Saretzki, Gabriele, Evans, Shane A, Salmonowicz, Hanna, Hruby, Adam, Geh, Daniel, Pavelko, Kevin D, Dolan, David, Reeves, Helen L, Grellscheid, Sushma, Wilson, Colin H, Pandanaboyana, Sanjay, Doolittle, Madison, Zglinicki, Thomas, Oakley, Fiona, Gallage, Suchira, Wilson, Caroline L, Birch, Jodie, Carroll, Bernadette, Chapman, James, Heikenwalder, Mathias, Neretti, Nicola, Khosla, Sundeep, Masuda, Claudio Akio, Tchkonia, Tamar, Kirkland, James L, Jurk, Diana, Mann, Derek A & Passos, João F (2021). Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner. The EMBO Journal 40(9): e106048.
• Vietri, Marina, Schultz, Sebastian W., Bellanger, Aurélie, Jones, Carl M., Petersen, Louise I., Raiborg, Camilla, Skarpen, Ellen, Pedurupillay, Christeen Ramane J., Kjos, Ingrid, Kip, Eline, Timmer, Romy, Jain, Ashish, Collas, Philippe, Knorr, Roland L., Grellscheid, Sushma N., Kusumaatmaja, Halim, Brech, Andreas, Micci, Francesca, Stenmark, Harald & Campsteijn, Coen (2020). Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation. Nature Cell Biology 22(7): 856-867.
• Mellough, Carla B., Bauer, Roman, Collin, Joseph, Dorgau, Birthe, Zerti, Darin, Dolan, David W. P., Jones, Carl M., Izuogu, Osagie G., Yu, Min, Hallam, Dean, Steyn, Jannetta S., White, Kathryn, Steel, David H., Santibanez-Koref, Mauro, Elliott, David J., Jackson, Michael S., Lindsay, Susan, Grellscheid, Sushma & Lako, Majlinda (2019). An integrated transcriptional analysis of the developing human retina. Development 146(2): dev169474.
• Ehrmann, Ingrid, Crichton, James H, Gazzara, Matthew R, James, Katherine, Liu, Yilei, Grellscheid, Sushma Nagaraja, Curk, Tomaž, de Rooij, Dirk, Steyn, Jannetta S, Cockell, Simon, Adams, Ian R, Barash, Yoseph & Elliott, David J (2019). An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning. eLife 8: e39304.
• da Silva, Paulo F. L., Ogrodnik, Mikolaj, Kucheryavenko, Olena, Glibert, Julien, Miwa, Satomi, Cameron, Kerry, Ishaq, Abbas, Saretzki, Gabriele, Nagaraja-Grellscheid, Sushma, Nelson, Glyn & von Zglinicki, Thomas (2019). The bystander effect contributes to the accumulation of senescent cells in vivo. Aging Cell 18(1): e12848.
• Buskin, Adriana, Zhu, Lili, Chichagova, Valeria, Basu, Basudha, Mozaffari-Jovin, Sina, Dolan, David, Droop, Alastair, Collin, Joseph, Bronstein, Revital, Mehrotra, Sudeep, Farkas, Michael, Hilgen, Gerrit, White, Kathryn, Pan, Kuan-Ting, Treumann, Achim, Hallam, Dean, Bialas, Katarzyna, Chung, Git, Mellough, Carla, Ding, Yuchun, Krasnogor, Natalio, Przyborski, Stefan, Zwolinski, Simon, Al-Aama, Jumana, Alharthi, Sameer, Xu, Yaobo, Wheway, Gabrielle, Szymanska, Katarzyna, McKibbin, Martin, Inglehearn, Chris F., Elliott, David J., Lindsay, Susan, Ali, Robin R., Steel, David H., Armstrong, Lyle, Sernagor, Evelyne, Urlaub, Henning, Pierce, Eric, Lührmann, Reinhard, Grellscheid, Sushma-Nagaraja, Johnson, Colin A. & Lako, Majlinda (2018). Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nature Communications 9(1): 4234.
• Lobine, D., Cummins, I., Govinden-Soulange, J., Ranghoo-Sanmukhiya, M., Lindsey, K., Chazot, P.L., Ambler, C.A., Grellscheid, S., Sharples, G., Lall, N., Lambrechts, I.A., Lavergne, C. & Howes, M.-J.R. (2018). Medicinal Mascarene Aloe s: An audit of their phytotherapeutic potential. Fitoterapia 124: 120-126.
• Ogrodnik, Mikolaj, Miwa, Satomi, Tchkonia, Tamar, Tiniakos, Dina, Wilson, Caroline L., Lahat, Albert, Day, Christoper P., Burt, Alastair, Palmer, Allyson, Anstee, Quentin M., Grellscheid, Sushma Nagaraja, Hoeijmakers, Jan H J., Barnhoorn, Sander, Mann, Derek A., Bird, Thomas G., Vermeij, Wilbert P., Kirkland, James L., Passos, João F., von Zglinicki, Thomas & Jurk, Diana (2017). Cellular senescence drives age-dependent hepatic steatosis. Nature Communications 8: 15691.
• Feracci, Mikael, Foot, Jaelle N., Grellscheid, Sushma N., Danilenko, Marina, Stehle, Ralf, Gonchar, Oksana, Kang, Hyun-Seo, Dalgliesh, Caroline, Meyer, N. Helge, Liu, Yilei, Lahat, Albert, Sattler, Michael, Eperon, Ian C., Elliott, David J. & Dominguez, Cyril (2016). Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68. Nature Communications 7: 10355.
• Ghosh, Pritha, Grellscheid, Sushma Nagaraja & Sowdhamini, R. (2016). A tale of two paralogs: human Transformer2 proteins with differential RNA-binding affinities. Journal of Biomolecular Structure and Dynamics 34(9): 1979-1986.
• Thien, A., Prentzell, M.T., Holzwarth, B., Kläsener, K., Kuper, I., Boehlke, C., Sonntag, A.G., Ruf, S., Maerz, L., Nitschke, R., Grellscheid, S.N., Reth, M., Walz, G., Baumeister, R., Neumann-Haefelin, E. & Thedieck, K. (2015). TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition. Developmental Cell 32(5): 617-630.
• Holly, A.C., Grellscheid, S.N., van de Walle, P., Dolan, D., Pilling, L.C., Daniels, D.J., von Zglinicki, T., Ferrucci, L., Melzer, D. & Harries, L.W. (2015). Comparison of senescence-associated miRNAs in primary skin and lung fibroblasts. Biogerontology
• Zupanic, A, Meplan, C, Grellscheid, SN, Mathers, JC, Kirkwood, TB, Hesketh, JE & Shanley, DP. (2014). Detecting translational regulation by change point analysis of ribosome profiling data sets. RNA 20(10): 1507-1518.
• Schmid, R., Grellscheid, S.N., Ehrmann, I., Dalgliesh, C., Danilenko, M., Paronetto, M.P., Pedrotti, S., Grellscheid, D., Dixon, R.J., Sette, C., Eperon, I.C. & Elliott, D.J. (2013). The splicing landscape is globally reprogrammed during male meiosis. Nucleic Acids Research 41(22): 10170-10184.
• Thedieck, K, Holzwarth, B, Prentzell, MT, Boehlke,C, Kläsener, K, Ruf, S, Sonntag,AG, Maerz, L, Grellscheid,SN, Kremmer,E, Nitschke, R, Kuehn, EW,, Jonker, JW, Groen, AK, Reth, M, Hall, MN & Baumeister,R. (2013). Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells. Cell 154(4): 859-874.
• Elliott, DJ Best, A, Dalgliesh, C, Ehrmann, I & Grellscheid, S (2012). How does Tra2β protein regulate tissue-specific RNA splicing? Biochemical Society Transactions 40(4): 784-788.
• Rajan P, Dalgliesh C, Carling PJ, Buist T, Zhang C, Grellscheid SN, Armstrong K, Stockley J, Simillion C, Gaughan L, Kalna G, Zhang MQ, Robson CN,, Leung HY, & Elliott DJ. (2011). Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome. PLoS ONE 6(12): e29088.
• Grellscheid SN, Dalgliesh C, Rozanska A,, Grellscheid D, Bourgeois CF, Stévenin J, & Elliott DJ. (2011). Molecular design of a splicing switch responsive to the RNA binding protein Tra2β. Nucleic Acids Research 39(18): 8092-8104.
• Grellscheid S, Dalgliesh C Storbeck M, Best A, Liu Y, Jakubik M Mende Y, Ehrmann I Curk T, Rossbach K, Bourgeois CF Stévenin J, Grellscheid D, Jackson MS, Wirth B & Elliott DJ (2011). Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development. PLoS Genetics 7(12): e1002390.
• Brichta L, Garbes L, Jedrzejowska M, Grellscheid SN, Holker I, Zimmermann K & Wirth B. (2008). Nonsense-mediated messenger RNA decay of survival motor neuron 1 causes spinal muscular atrophy. Human Genetics 123(2): 141-153.
• Skrisovska L, Bourgeois CF, Stefl R, Grellscheid SN, Kister L, Wenter P, Elliott DJ, Stevenin J & Allain FH (2007). The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction. EMBO Reports 8(4): 372-379.
• Vukusic I., Grellscheid S.N. & Wiehe T. (2007). Applying genetic programming to the prediction of alternative mRNA splice variants. Genomics 89(4):): 471-479.
• Grellscheid SN & Smith CW. (2006). An apparent pseudo-exon acts both as an alternative exon that leads to nonsense-mediated decay and as a zero-length exon. Mol Cell Biol 26(6):): 2237-2246.