Staff profile

Journal Article

• Law, J. O., Jones, C. M., Stevenson, T., Williamson, T. A., Turner, M. S., Kusumaatmaja, H., & Grellscheid, S. N. (2023). A bending rigidity parameter for stress granule condensates. Science Advances, 9(20), https://doi.org/10.1126/sciadv.adg0432
• Thompson, H., Shen, W., Matus, R., Kakkar, M., Jones, C., Dolan, D., …Lindsey, K. (2023). MERISTEM-DEFECTIVE regulates the balance between stemness and differentiation in the root meristem through RNA splicing control. Development, 150(7), Article dev201476. https://doi.org/10.1242/dev.201476
• Abbas, M., Law, J. O., Grellscheid, S. N., Huck, W. T., & Spruijt, E. (2022). Peptide‐Based Coacervate‐Core Vesicles with Semipermeable Membranes. Advanced Materials, 34(34), Article 2202913. https://doi.org/10.1002/adma.202202913
• O’Hare, C. A., Matsos, V. G., Newton, J., Smith, K., Hochstetter, J., Jaiswar, R., …Bœhm, C. (2022). Particle detection and tracking with DNA. The European Physical Journal C, 82(4), Article 306. https://doi.org/10.1140/epjc/s10052-022-10264-6
• Lagnado, A., Leslie, J., Ruchaud‐Sparagano, M., Victorelli, S., Hirsova, P., Ogrodnik, M., …Passos, J. F. (2021). Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner. The EMBO Journal, 40(9), Article e106048. https://doi.org/10.15252/embj.2020106048
• Chyżyńska, K., Labun, K., Jones, C., Grellscheid, S. N., & Valen, E. (2021). Deep conservation of ribosome stall sites across RNA processing genes. NAR Genomics and Bioinformatics, 3(2), https://doi.org/10.1093/nargab/lqab038
• Vietri, M., Schultz, S. W., Bellanger, A., Jones, C. M., Petersen, L. I., Raiborg, C., …Campsteijn, C. (2020). Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation. Nature Cell Biology, 22(7), 856-867. https://doi.org/10.1038/s41556-020-0537-5
• da Silva, P. F., Ogrodnik, M., Kucheryavenko, O., Glibert, J., Miwa, S., Cameron, K., …von Zglinicki, T. (2019). The bystander effect contributes to the accumulation of senescent cells in vivo. Aging Cell, 18(1), Article e12848. https://doi.org/10.1111/acel.12848
• Ehrmann, I., Crichton, J. H., Gazzara, M. R., James, K., Liu, Y., Grellscheid, S. N., …Elliott, D. J. (2019). An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning. eLife, 8, Article e39304. https://doi.org/10.7554/elife.39304
• Mellough, C. B., Bauer, R., Collin, J., Dorgau, B., Zerti, D., Dolan, D. W., …Lako, M. (2019). An integrated transcriptional analysis of the developing human retina. Development, 146(2), Article dev169474. https://doi.org/10.1242/dev.169474
• Buskin, A., Zhu, L., Chichagova, V., Basu, B., Mozaffari-Jovin, S., Dolan, D., …Lako, M. (2018). Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nature Communications, 9(1), Article 4234. https://doi.org/10.1038/s41467-018-06448-y
• Lobine, D., Cummins, I., Govinden-Soulange, J., Ranghoo-Sanmukhiya, M., Lindsey, K., Chazot, P., …Howes, M. (2018). Medicinal Mascarene Aloe s: An audit of their phytotherapeutic potential. Fitoterapia, 124, 120-126. https://doi.org/10.1016/j.fitote.2017.10.010
• Ogrodnik, M., Miwa, S., Tchkonia, T., Tiniakos, D., Wilson, C. L., Lahat, A., …Jurk, D. (2017). Cellular senescence drives age-dependent hepatic steatosis. Nature Communications, 8, https://doi.org/10.1038/ncomms15691
• Ghosh, P., Grellscheid, S. N., & Sowdhamini, R. (2016). A tale of two paralogs: human Transformer2 proteins with differential RNA-binding affinities. Journal of Biomolecular Structure and Dynamics, 34(9), 1979-1986. https://doi.org/10.1080/07391102.2015.1100551
• Feracci, M., Foot, J. N., Grellscheid, S. N., Danilenko, M., Stehle, R., Gonchar, O., …Dominguez, C. (2016). Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68. Nature Communications, 7, Article 10355. https://doi.org/10.1038/ncomms10355
• Thien, A., Prentzell, M., Holzwarth, B., Kläsener, K., Kuper, I., Boehlke, C., …Thedieck, K. (2015). TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition. Developmental Cell, 32(5), 617-630. https://doi.org/10.1016/j.devcel.2015.01.026
• Holly, A., Grellscheid, S., van de Walle, P., Dolan, D., Pilling, L., Daniels, D., …Harries, L. (2015). Comparison of senescence-associated miRNAs in primary skin and lung fibroblasts. Biogerontology, https://doi.org/10.1007/s10522-015-9560-5
• Zupanic, A., Meplan, C., Grellscheid, S., Mathers, J., Kirkwood, T., Hesketh, J., & Shanley, D. (2014). Detecting translational regulation by change point analysis of ribosome profiling data sets. RNA, 20(10), 1507-1518. https://doi.org/10.1261/rna.045286.114
• Schmid, R., Grellscheid, S., Ehrmann, I., Dalgliesh, C., Danilenko, M., Paronetto, M., …Elliott, D. (2013). The splicing landscape is globally reprogrammed during male meiosis. Nucleic Acids Research, 41(22), 10170-10184. https://doi.org/10.1093/nar/gkt811
• Thedieck, K., Holzwarth, B., Prentzell, M., Boehlke, C., Kläsener, K., Ruf, S., …Baumeister, R. (2013). Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells. Cell, 154(4), 859-874. https://doi.org/10.1016/j.cell.2013.07.031
• Elliott, D., Best, A., Dalgliesh, C., Ehrmann, I., & Grellscheid, S. (2012). How does Tra2β protein regulate tissue-specific RNA splicing?. Biochemical Society Transactions, 40(4), 784-788. https://doi.org/10.1042/bst20120036
• Rajan, P., Dalgliesh, C., Carling, P., Buist, T., Zhang, C., Grellscheid, S., …Elliott, D. (2011). Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome. PLoS ONE, 6(12), Article e29088. https://doi.org/10.1371/journal.pone.0029088
• Grellscheid, S., Dalgliesh, C., Storbeck, M., Best, A., Liu, Y., Jakubik, M., …Elliott, D. (2011). Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development. PLoS Genetics, 7(12), Article e1002390. https://doi.org/10.1371/journal.pgen.1002390
• Grellscheid, S., Dalgliesh, C., Rozanska, A., Grellscheid, D., Bourgeois, C., Stévenin, J., & Elliott, D. (2011). Molecular design of a splicing switch responsive to the RNA binding protein Tra2β. Nucleic Acids Research, 39(18), 8092-8104. https://doi.org/10.1093/nar/gkr495
• Brichta, L., Garbes, L., Jedrzejowska, M., Grellscheid, S., Holker, I., Zimmermann, K., & Wirth, B. (2008). Nonsense-mediated messenger RNA decay of survival motor neuron 1 causes spinal muscular atrophy. Human Genetics, 123(2), 141-153. https://doi.org/10.1007/s00439-007-0455-7
• Vukusic, I., Grellscheid, S., & Wiehe, T. (2007). Applying genetic programming to the prediction of alternative mRNA splice variants. Genomics, 89((4):), 471-479
• Skrisovska, L., Bourgeois, C., Stefl, R., Grellscheid, S., Kister, L., Wenter, P., …Allain, F. (2007). The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction. EMBO Reports, 8(4), 372-379. https://doi.org/10.1038/sj.embor.7400910
• Grellscheid, S., & Smith, C. (2006). An apparent pseudo-exon acts both as an alternative exon that leads to nonsense-mediated decay and as a zero-length exon