Staff profile

Daphne Jackson Fellowship 2009 - 2011

• Crystallography
• Molecular Biology
• Biophysical Methods

Journal Article

• Jasilionis, Andrius, Plotka, Magdalena, Wang, Lei, Dorawa, Sebastian, Lange, Joanna, Watzlawick, Hildegard, van den Bergh, Tom, Vroling, Bas, Altenbuchner, Josef, Kaczorowska, Anna‐Karina, Pohl, Ehmke, Kaczorowski, Tadeusz, Nordberg Karlsson, Eva & Freitag‐Pohl, Stefanie (2023). AmiP from hyperthermophilic Thermus parvatiensis prophage is a thermoactive and ultrathermostable peptidoglycan lytic amidase. Protein Science 32(3): e4585.
• Escrivani, Douglas O., Charlton, Rebecca L., Caruso, Marjolly B., Burle-Caldas, Gabriela A., Borsodi, Maria Paula G., Zingali, Russolina B., Arruda-Costa, Natalia, Palmeira-Mello, Marcos V., de Jesus, Jéssica B., Souza, Alessandra M. T., Abrahim-Vieira, Bárbara, Freitag-Pohl, Stefanie, Pohl, Ehmke, Denny, Paul W., Rossi-Bergmann, Bartira & Steel, Patrick G. (2021). Chalcones identify cTXNPx as a potential antileishmanial drug target. PLOS Neglected Tropical Diseases 15(11): e0009951.
• Schwarz, Maria, Eno, Rebecca F. M., Freitag-Pohl, Stefanie, Coxon, Christopher R., Straker, Hannah E., Wortley, David J., Hughes, David J., Mitchell, Glynn, Moore, Jenny, Cummins, Ian, Onkokesung, Nawaporn, Brazier-Hicks, Melissa, Edwards, Robert, Pohl, Ehmke & Steel, Patrick G. (2021). Flavonoid-based inhibitors of the Phi-class glutathione transferase from black-grass to combat multiple herbicide resistance. Organic & Biomolecular Chemistry 19(42): 9211-9222.
• Andrews, Jessica L., Nilsson Lill, Sten O., Freitag-Pohl, Stefanie, Apperley, David C., Yufit, Dmitry S., Batsanov, Andrei S., Mulvee, Matthew T., Edkins, Katharina, McCabe, James F., Berry, David J., Probert, Michael R. & Steed, Jonathan W. (2021). Derisking the Polymorph Landscape: The Complex Polymorphism of Mexiletine Hydrochloride. Crystal Growth & Design 21(12): 7150-7167.
• Aevarsson, Arnthor, Kaczorowska, Anna-Karina, Adalsteinsson, Bjorn Thor, Ahlqvist, Josefin, Al-Karadaghi, Salam, Altenbuchner, Joseph, Arsin, Hasan, Atlasson, Ulfur August, Brandt, David, Cichowicz-Cieslak, Magdalena, Cornish, Katy A. S., Courtin, Jeremy, Dabrowski, Slawomir, Dahle, Hakon, Djeffane, Samia, Dorawa, Sebastian, Dusaucy, Julia, Enault, Francois, Fedoy, Anita-Elin, Freitag-Pohl, Stefanie, Fridjonsson, Olafur H., Galiez, Clovis, Glomsaker, Eirin, Guerin, Mickael, Gundeso, Sigurd E., Gudmundsdottir, Elisabet E., Gudmundsson, Hordur, Hakansson, Maria, Henke, Christian, Helleux, Alexandra, Henriksen, Jorn Remi, Hjorleifdottir, Sigridur, Hreggvidsson, Gudmundur O., Jasilionis, Andrius, Jochheim, Annika, Jonsdottir, Ilmur, Jonsdottir, Lilja Bjork, Jurczak-Kurek, Agata, Kaczorowski, Tadeusz, Kalinowski, Jorn, Kozlowski, Lukasz P., Krupovic, Mart, Kwiatkowska-Semrau, Karolina, Lanes, Olav, Lange, Joanna, Lebrat, Julien, Linares-Pasten, Javier, Liu, Ying, Lorentsen, Steffen A., Lutterman, Tobias, Mas, Thibaud, Merre, William, Mirdita, Milot, Morzywolek, Agnieszka, Ndela, Eric Olo, Karlsson, Eva Nordberg, Olgudottir, Edda, Pedersen, Cathrine, Perler, Francine, Petursdottir, Solveig K., Plotka, Magdalena, Pohl, Ehmke, Prangishvili, David, Ray, Jessica L., Reynisson, Birkir, Robertsdottir, Tara, Sandaa, Ruth-Anne, Sczyrba, Alexander, Skirnisdottir, Sigurlaug, Soding, Johannes, Solstad, Terese, Steen, Ida H., Stefansson, Sigmar Karl, Steinegger, Martin, Overa, Katrine Stange, Striberny, Bernd, Svensson, Anders, Szadkowska, Monika, Tarrant, Emma J., Terzian, Paul, Tourigny, Mathilde, van den Bergh, Tom, Vanhalst, Justine, Vincent, Jonathan, Vroling, Bas, Walse, Bjorn, Wang, Lei, Watzlawick, Hildegard, Welin, Martin, Werbowy, Olesia, Wons, Ewa & Zhang, Ruoshi (2021). Going to extremes - a metagenomic journey into the dark matter of life. FEMS MICROBIOLOGY LETTERS 368(12): fnab067.
• Zohib, Muhammad, Maheshwari, Diva, Pal, Ravi Kant, Freitag-Pohl, Stefanie, Biswal, Bichitra Kumar, Pohl, Ehmke & Arora, Ashish (2020). Crystal structure of the GDP-bound GTPase domain of Rab5a from Leishmania donovani. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 76(11): 544-556.
• Bruce, D, Cardew, E, Freitag-Pohl, S & Pohl, E (2019). How to Stabilize Protein: Stability Screens for Thermal Shift Assays and Nano Differential Scanning Fluorimetry in the Virus-X Project. JoVE - journal of visualized experiments 144: e58666.
• Freitag-Pohl, Stefanie, Jasilionis, Andrius, Håkansson, Maria, Svensson, L. Anders, Kovačič, Rebeka, Welin, Martin, Watzlawick, Hildegard, Wang, Lei, Altenbuchner, Josef, Płotka, Magdalena, Kaczorowska, Anna Karina, Kaczorowski, Tadeusz, Nordberg Karlsson, Eva, Al-Karadaghi, Salam, Walse, Björn, Aevarsson, Arnthór & Pohl, Ehmke (2019). Crystal structures of the Bacillus subtilis prophage lytic cassette proteins XepA and YomS. Acta Crystallographica Section D Structural Biology 75(11): 1028-1039.
• Le Trong, I, Freitag, S, Klumb, LA, Chu, V, Stayton, PS & Stenkamp, RE (2003). Structural studies of hydrogen bonds in the high-affinity streptavidin-biotin complex: mutations of amino acids interacting with the ureido oxygen of biotin. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 59(9): 1567-1573.
• Hyre, DE, Le Trong, I, Freitag, S, Stenkamp, RE & Stayton, PS (2000). Ser45 plays an important role in managing both the equilibrium and transition state energetics of the streptavidin-biotin system. PROTEIN SCIENCE 9(5): 878-885.
• Stayton, PS, Freitag, S, Klumb, LA, Chilkoti, A, Chu, V, Penzotti, JE, To, R, Hyre, D, Le Trong, I, Lybrand, TP & Stenkamp, RE (1999). Streptavidin-biotin binding energetics. BIOMOLECULAR ENGINEERING 16(1-4): 39-44.
• Freitag, S, Le Trong, I, Klumb, LA, Stayton, PS & Stenkamp, RE (1999). Atomic resolution structure of biotin-free Tyr43Phe streptavidin: what is in the binding site? ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 55(6): 1118-1126.
• Freitag, S, Chu, V, Penzotti, JE, Klumb, LA, To, R, Hyre, D, Le Trong, I, Lybrand, TP, Stenkamp, RE & Stayton, PS (1999). A structural snapshot of an intermediate on the streptavidin-biotin dissociation pathway. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(15): 8384-8389.
• Freitag, S, Le Trong, I, Klumb, LA, Chu, V, Chilkoti, A, Stayton, PS & Stenkamp, RE (1999). X-ray crystallographic studies of streptavidin mutants binding to biotin. BIOMOLECULAR ENGINEERING 16(1-4): 13-19.
• Freitag, S, Le Trong, I, Chilkoti, A, Klumb, LA, Stayton, PS & Stenkamp, RE (1998). Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex. JOURNAL OF MOLECULAR BIOLOGY 279(1): 211-221.
• Chu, V, Freitag, S, Le Trong, I, Stenkamp, RE & Stayton, PS (1998). Thermodynamic and structural consequences of flexible loop deletion by circular permutation in the streptavidin-biotin system. PROTEIN SCIENCE 7(4): 848-859.
• Fleischer, R, Freitag, S & Stalke, D (1998). Oxidation of [Li-4\(NBut)(3)S\(2)]: a new route to sulfur triimides. JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS (2): 193-197.
• Freitag, S, LeTrong, I, Klumb, L, Stayton, PS & Stenkamp, RE (1997). Structural studies of the streptavidin binding loop. PROTEIN SCIENCE 6(6): 1157-1166.
• Freitag, S, HerbstIrmer, R, Lameyer, L & Stalke, D (1996). Observation of a Ge-Li bond: Donor-base-stabilized (tris(trimethylsilyl)germyl)lithium. ORGANOMETALLICS 15(12): 2839-2841.
• Ossig, G, Meller, A, Freitag, S, Muller, O, Gornitzka, H & HerbstIrmer, R (1996). Products of the reactions of 2-diazomalonate and of 2-diazoindanedione with germylenes and stannylenes. ORGANOMETALLICS 15(1): 408-414.
• Freitag, S & HerbstIrmer, R (1996). Crystal structure of chloro-dimethylstannyl-diphenylphosphinoyl-ethan-phosphonaciddiisopropyl ester, C22H33ClO4P2Sn. ZEITSCHRIFT FUR KRISTALLOGRAPHIE 211(11): 859-860.
• Fleischer, R, Freitag, S, Pauer, F & Stalke, D (1996). [S(NtBu)(3)](2-) - A cap-shaped dianion, isoelectronic with the sulfite ion and oxidizable to a stable radical anion. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH 35(2): 204-206.
• Hemme, I, Klingebiel, U, Freitag, S & Stalke, D (1995). Monomeric trilithium-tris[tert-butyldimethylsilylamido]phenylsilane, PhSi[NLi(thf)SiMe(2)CMe(3)](3) - Synthesis and crystal structure. ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE 621(12): 2093-2096.
• FREITAG, S, HERBSTIRMER, R, AHLEMANN, JT & ROESKY, HW (1995). (N-(1-ADAMANTYL)[(PENTAFLUORO-2-PROPENYL)THIO]AMINO)(FLUORO)BIS[2,4, 6-TRIS(TRIFLUOROMETHYL)PHENYL]TIN AT 153 K. ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS 51(4): 631-633.
• VOELKER, H, FREITAG, S, PIEPER, U & ROESKY, HW (1995). SYNTHESIS OF THE NEW SILANEDIYLDIPHOSPHINITE TBU(2)SI(OPPH(2)(2) AND ITS REACTIONS WITH THE NORBORNADIENE COMPLEXES C(7)H(8)M(CO)(4) (M=CR, MO, W) - CRYSTAL-STRUCTURES OF CIS-M(CO)(4),[TBU(2)SI(OPPH(2)(2)] (M=CR, MO). ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE 621(4): 694-698.
• DROST, C, JAGER, C, FREITAG, S, KLINGEBIEL, U, NOLTEMEYER, M & SHELDRICK, GM (1994). DILITHIUM N,N'-BIS(TRIMETHYLSILYL)HYDRAZIDE AND A HYDROLYSIS PRODUCT - SIDE-ON-COORDINATED AND END-ON-COORDINATED LI CATIONS TO N2(2-) AND O2(2-). CHEMISCHE BERICHTE 127(5): 845-847.
• FREITAG, S, HERBSTIRMER, R, RICHTER, FU & WEICHMANN, H (1994). TETRAISOPROPYL 2-[(BROMO)(CHLORO)(METHYL)STANNYL]-1,1-ETHANEDIPHOSPHONATE AT 153K. ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS 50(10): 1588-1590.
• RAUBOLD, T, FREITAG, S, HERBSTIRMER, R & ROESKY, HW (1993). SYNTHESIS AND CRYSTAL-STRUCTURE OF THE SPIROCYCLE [(I-PR)2P(S)NSIME3]2SNCL2. ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE 619(5): 951-953.
• FREITAG, S, KOLODZIEJSKI, W, PAUER, F & STALKE, D (1993). IMINOAMINOSULFINATES - SYNTHESIS, CRYSTAL-STRUCTURES, AND REARRANGEMENT MONITORED BY LI-7 SOLID-STATE NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY. JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS (23): 3479-3488.
• OSSIG, G, MELLER, A, FREITAG, S & HERBSTIRMER, R (1993). SYNTHESIS AND X-RAY CRYSTAL-STRUCTURE OF A STANNAIMINE. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS (6): 497-499.
• OSSIG, G, MELLER, A, FREITAG, S, HERBSTIRMER, R & SHELDRICK, GM (1993). REACTIONS OF A FREE STANNAIMINE AND OF BASE-STABILIZED STANNYLENES. CHEMISCHE BERICHTE-RECUEIL 126(10): 2247-2253.
• GRUTZMACHER, H, FREITAG, S, HERBSTIRMER, R & SHELDRICK, GS (1992). INVESTIGATIONS OF THE STRUCTURE AND REACTIVITY OF A STANNAKETENIMINE. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH 31(4): 437-438.
• MAY, A, ROESKY, HW, HERBSTIRMER, R, FREITAG, S & SHELDRICK, GM (1992). [3 + 1] CYCLOADDITION - REACTION OF DICHLOROGERMYLENE WITH HEXAFLUORO-2-PROPANETHIONE 1-ADAMANTYLIMIDE. ORGANOMETALLICS 11(1): 15-16.
• MELLER, A, OSSIG, G, MARINGGELE, W, NOLTEMEYER, M, STALKE, D, HERBSTIRMER, R, FREITAG, S & SHELDRICK, GM (1992). REACTIONS OF GERMYLENES WITH ACID AZIDES. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES 47(2): 162-170.
• MELLER, A, OSSIG, G, MARINGGELE, W, STALKE, D, HERBSTIRMER, R, FREITAG, S & SHELDRICK, GM (1991). SYNTHESIS AND X-RAY CRYSTAL-STRUCTURE OF GERMAIMINES. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS (16): 1123-1124.