Staff profile

Ph.D. Technical University of Darmstadt, Darmstadt, Germany, 1996. Postdoctoral Fellow, Howard Hughes Medical Institute and Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, USA, 1997 - 2004.

• Molecular Biology
• Yeast Genetics
• Unfolded Protein Response

• Biomolecular Interactions

• Personal Home Page

Authored book

• M. Schröder (2010). Molecular chaperones of the endoplasmic reticulum. Hauppage, NY: NOVA Science Publishers.
• M. Schröder (1997). Identifikation limitierter Schritte der Antithrombin III Produktion in genamplifizierten CHO-Zellen. Aachen: Shaker Verlag.

Chapter in book

• M. Schröder (2009). Molecular chaperones of the endoplasmic reticulum. In Handbook of Molecular Chaperones: Roles, Structures and Mechanisms. P. Durante & L. Colucci Hauppage, NY: NOVA Science Publishers. 1-78.
• M. Schröder (2008). Unfolded protein response. In Yearbook of Science and Technology. J. Weil, D. Blumel, S. Malmoli & J. Netting New York: McGraw-Hill. 356-360.
• M. Schröder (2007). The cellular response to protein unfolding stress. In BMS Symposium Series, Exploitation of Fungi. G. D. Robson, P. van West & G. M. Gadd Cambridge: Cambridge University Press. 26: 117-139.
• Frech, M., Mikosch, T., Schröder, M. & Stassen, M. (2007). Allgemeine Methoden. In Gentechnische Methoden: eine Sammlung von Arbeitsanleitungen für das molekularbiologische Labor. Jansohn, M. Munich: Elsevier. 1-35.
• M. Schröder (2007). Isolierung von RNA. In Gentechnische Methoden. Jansohn, M. Munich: Elsevier. 131-154.
• N. Strudwick & M. Schröder (2007). The unfolded protein response. In Cell Engineering Vol 5: Systems Biology. M. Al-Rubeai & M. Fussenegger Dordrecht: Springer Netherlands. 5: 69-157.
• M. Schröder (2002). Isolierung von RNA. In Gentechnische Methoden. G. Schrimpf Heidelberg: Spektrum Academischer Verlag. 129-145.
• Frech, M., Mikosch, T., Schröder, M. & Stassen, M. (2002). Allgemeine Methoden. In Gentechnische Methoden: eine Sammlung von Arbeitsanleitungen für das molekularbiologische Labor. Schrimpf, G. & Aigner, A. Heidelberg: Spektrum Akademischer Verlag. 1-37.
• M. Schröder (1999). Isolierung von RNA. In Genrechnische Methoden. H. G. Gassen & G. Schrimpf Heidelberg: Spektrum Akademischer Verlag. 225-242.
• G. Schrimpf, M. Schröder, E. Weitnauer & P. Friedl (1995). Metabolism of confluent vascular endothelial cell cultures. In Animal Cell Technology: Developments towards the 21st century. E. C. Beuvery, J. B. Griffiths & W. P. Zeijlemaker Dordrecht: Kluwer Academic Publishers. 1127-1131.

Journal Article

• Read, Adam & Schröder, Martin (2021). The Unfolded Protein Response: An Overview. Biology 10(5): 384.
• Brown, Max, Dainty, Samantha, Strudwick, Natalie, Mihai, Adina D., Watson, Jamie N., Dendooven, Robina, Paton, Adrienne W., Paton, James C. & Schröder, Martin (2020). Endoplasmic reticulum stress causes insulin resistance by inhibiting delivery of newly synthesised insulin receptors to the cell surface. Molecular Biology of the Cell 31(23): 2495-2629.
• Armstrong, M. C., Sestak, S., Ali, A. A., Sagini, H. A. M., Brown, M., Baty, K., Treumann, A. & Schröder, M. (2017). Bypass of activation loop phosphorylation by aspartate 836 in activation of the endoribonuclease activity of Ire1. Molecular and Cellular Biology 37(16): e00655-16.
• Brown, M., Strudwick, N., Suwara, M., Sutcliffe, L. K., Mihai, A. D., Ali, A. A., Watson, J. N. & Schröder, M. (2016). An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response. Journal of Cell Science 129(12): 2317-2328.
• Mihai, A. D. & Schröder, M. (2015). Glucose starvation and hypoxia, but not the saturated fatty acid palmitic acid or cholesterol, activate the unfolded protein response in 3T3-F442A and 3T3-L1 adipocytes. Adipocyte 4(3): 188-202.
• Skipsey, M., Hack, G., Hooper, T. A., Shankey, M. C., Conway, L. P., Schröder, M. & Hodgson, D. R. W. (2013). 5’-Deoxy-5’-hydrazinylguanosine as an initiator of T7 RNA polymerase-catalyzed transcriptions for the preparation of labeling-ready RNAs. Nucleosides, Nucleotides, and Nucleic Acids 32(12): 670-681.
• D. R. W. Hodgson & M. Schröder (2011). Chemical approaches twoards unraveling kinase-mediated signaling pathways. Chemical Society Reviews 40(3): 1211-1223.
• D. Cox, N. Srudwick, A. A. Ali, A. W. Paton, J. C. Paton & M. Schröder (2011). Measuring signaling by the unfolded protein response. Methods in Enzymology 491: 261-292.
• M. Schröder & L. Sutcliffe (2010). Consequences of stress in the secretory pathway: the ER stress response and its role in the metabolic syndrome. Methods in Molecular Biology 648: 43-62.
• N. Strudwick, M. Brown, V. M. Parmar & M. Schröder (2010). Ime1 and Ime2 are required for pseudohyphal growth of Saccharomyces cerevisiae on Nonfermentable Carbon Sources. Molecular and Cellular Biology 30(23): 5514-5530.
• M. Schröder (2008). Endoplasmic reticulum stress responses. Cellular and Molecular Life Sciences 65(6): 862-894.
• M. Schröder (2008). Engineering eukaryotic protein factories. Biotechnology Letters 30(2): 187-196.
• S. U. Khan & M. Schröder (2008). Engineering of chaperone systems and of the unfolded protein response. Cytotechnology 57(3): 207-231.
• M. E. Schröder & R. J. Kaufman (2007). Ire1. UCSD-Nature Molecule Pages
• M. Schröder & K. Kohno (2007). Recent advances in understanding the unfolded protein response. Antioxidants and Redox Signaling 9(12): 2241-2244.
• M. Schröder & R. J. Kaufman (2006). Divergent roles for IRE1α and PERK in the unfolded protein response. Current Molecular Medicine 6(1): 5-36.
• M. Schröder (2006). The unfolded protein response. Molecular Biotechnology 34(2): 279-290.
• M. Schröder & R. J. Kaufman (2005). The mammalian unfolded protein response. Annual Review of Biochemistry 74: 739-789.
• M. Schröder & R. J. Kaufman (2005). ER stress and the unfolded protein response. Mutation Research 569(1-2): 29-63.
• S. H. Back, M. Schröder, K. Lee, K. Zhang & R. J. Kaufman (2005). ER stress signalling by regulated splicing: IRE1/HAC1/XBP1. Methods 35(4): 395-416.
• M. Schröder, K. Matischak & P. Friedl (2004). Serum- and protein-free media formulations for the Chinese hamster ovary cell line DUKXB11. Journal of Biotechnology 108(3): 279-292.
• M. Schröder, R. Clark, C. Y. Liu & R. J. Kaufman (2004). The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase. EMBO Journal 23(11): 2281-2292.
• C. Wiederkehr, R. Basavaraj, C. Sarrauste de Menthiere, L. Hermida, R. Koch, U. Schlecht, A. Amon, S. Brachat, M. Breitenbach, P. Briza, S. Caburet, M. Cherry, R. Davis, A. Deutschbauer, H. G. Dickinson, T. Dumitrescu, M. Fellous, A. Goldman, J. A. Grootegoed, R. Hawley, R. Ishii, B. Jegou, R. J. Kaufman, F. Klein, N. Lamb, B. Maro, K. Nasmyth, A. Nicolas, T. Orr-Weaver, P. Philippsen, C. Pineau, K. P. Rabitsch, V. Reinke, H. Roest, W. Saunders, M. Schröder, T. Schedl, M. Siep, A. Villeneuve, D. J. Wolgemuth, M. Yamamoto, D. Zickler, R. E. Esposito & M. Primig (2004). GermOnline, a cross-species knowledgebase on germ cell differentiation. Nucleic Acids Research 32(Database issue): D560-D567.
• M. Schröder, R. Clark & R. J. Kaufman (2003). IRE1- and HAC1-independent transcriptional regulation in the unfolded protein response of yeast. Molecular Microbiology 49(3): 591-606.
• M. Schröder, R. Schäfer & P. Friedl (2002). Induction of protein aggregation in an early secretory compartment by elevation of expression level. Biotechnology and Bioengineering 78(2): 131-140.
• R. J. Kaufman, D. Scheuner, M. Schröder, X. Shen, K. Lee, C. Y. Liu & S. M. Arnold (2002). The unfolded protein response in nutrient sensing and differentiation. Nature Reviews Molecular Cell Biology 3(6): 411-421.
• C. Y. Liu, M. Schröder & R. J. Kaufman (2000). Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum. Journal of Biological Chemistry 275(32): 24881-24885.
• M. Schröder, J. S. Chang & R. J. Kaufman (2000). The unfolded protein response represses nitrogen-starvation induced developmental differentiation in yeast. Genes and Development 14(23): 2962-2975.
• M. Schröder, C. Körner & P. Friedl (1999). Quantitative analysis of transcription and translation in gene amplified Chinese hamster ovary cells on the basis of a kinetic model. Cytotechnology 29(2): 93-102.
• M. Schröder & P. Friedl (1997). A protein-free solution as replacement for serum in trypsinization protocols for anchorage-dependent cells. Methods in Cell Science 19(2): 137-147.
• M. Schröder, R. Schäfer & P. Friedl (1997). Spectrophotometric determination of iodixanol in subcellular fractions of mammalian cells. Analytical Biochemistry 244(1): 174-176.
• M. Schröder & P. Friedl (1997). Enzymatic determination of D-glucose in cell culture media using glucose oxidase, horseradish peroxidase and 3,3 ',5,5 '- tetramethylbenzidine. The Genetic Engineer and Biotechnologist 17(4): 157-163.
• M. Schröder & P. Friedl (1997). Overexpression of recombinant human antithrombin III in Chinese hamster ovary cells results in malformation and decreased secretion of the recombinant protein. Biotechnology and Bioengineering 53(6): 547-559.
• M. Schröder, D. Kaiser, R. Schäfer & P. Friedl (1996). Indirect sandwich ELISA for human antithrombin III employing the interaction between D-biotin and streptavidin. The Genetic Engineer and Biotechnologist 16(4): 211-225.
• G. Schrimpf, M. Schröder, E. Weitnauer & P. Friedl (1994). Metabolic rates of vascular endothelial cells in vitro. Cytotechnology 16(1): 43-50.