Staff profile

I have worked as a bioinformatician for 21 years and have 9 years of experience of analysing next generation sequencing data. I re-joined the Department of Biosciences in 2019. I manage the Bioinformatics Facility and teach BIOL40715: Bioinformatics and Data Science and BIOL50315: Bioinformatics. I supervise students working on DATA40345: Data Science Research Project.

• Application of bioinformatics to biomedical research
• Analysis of next generation sequencing data
• Application of bioinformatics to biological research

• BIOL50315: Bioinformatics
• Appsanywhere
• Bioinformatics Facility
• Bioinformatics on Durham University SharePoint
• BIOL40715: Bioinformatics and Data Science
• BIOL50415: Modelling in Molecular Biology
• BUSI4S115: Strategic Leadership
• COMP41815: Introduction to Computer Science
• COMP42315: Programming for Data Science
• COMP42415: Text Mining and Language Analytics
• DATA40345
• Master of Data Science (Bioinformatics and Biological Modelling)
• MATH42515: Data Exploration, Visualization, and Unsupervised Learning
• MATH42615: Introduction to Mathematics for Data Science
• MATH42715: Introduction to Statistics for Data Science
• MATH42815: Machine Learning
• PHIL42415: Ethics and Bias in Data Science
• Plant Biotechnology and Enterprise
• Postgraduate Modules
• Time table
• ULTRA

• 0000: h-index 45:
• 0000: Over 100 peer-reviewed journal papers:

Journal Article

• Lakmes, Abdulkarim, Jhar, Abdullah, Penmetsa, R. Varma, Wei, Wenbin, Brennan, Adrian C. & Kahriman, Abdullah (2023). Inheritance of seed weight and growth habit in 10 intercross chickpea (Cicer arietinum) nested association mapping populations. Plant Breeding 142(1): 86-96.
• Alpizer-Sosa, E.A., Ithnin, N.R.B., Wei, W., Pountain, A.W., Weidt, A.K., Donachie, A.M., Ritchie, R., Dickie, E.A, Burchmore, R.J.S., Denny, P.W. & Barrett, M.P. (2022). Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response. PLOS Neglected Tropical Diseases 16(9): e0010779.
• Alpizar-Sosa, E.A., Kumordzi, Y., Wei, W., Whitfield, P., Barrett, M.P. & Denny, P.W. (2022). Genome deletions to overcome the directed loss of gene function in Leishmania. Frontiers in Cellular and Infection Microbiology, section Parasite and Host 12.
• Lakmes, A., Jhar, A., Penmetsa, R.V., Wei, W.,, Brennan, A.C., & Kahriman, A. (2022). The Quantitative Genetics of Flowering Traits in Wide Crosses of Chickpea. Agriculture 12(4): 486.
• Kalesh, K., Wei, W., Mantilla, B.S., Roumeliotis, T.I., Choudhary, J. & Denny, P. W. (2022). Transcriptome-Wide Identification of Coding and Noncoding RNA-Binding Proteins Defines the Comprehensive RNA Interactome of Leishmania mexicana. Microbiology Spectrum 10(1): e0242221.
• Larbalestier, H., Keatinge, M.,, Watson, L.,, White, E.,, Gowda, S.,, Wei, W.,, Koler, K.,, Semenova, S.A., Elkin, A.M.,, Rimmer, N., Sweeney, S.T.,, Mazzolini, J.,, Sieger, D.,, Hide, W.,, McDearmid, J.,, Panula, P., MacDonald, R.B., & Bandmann, O. (2022). GCH1 Deficiency Activates Brain Innate Immune Response and Impairs Tyrosine Hydroxylase Homeostasis. Journal of Neuroscience 42(4): 702-716.
• An, Haiyan, Litscher, Gioana, Watanabe, Naruaki, Wei, Wenbin, Hashimoto, Tadafumi, Iwatsubo, Takeshi, Buchman, Vladimir L. & Shelkovnikova, Tatyana A. (2022). ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity. Neurobiology of Disease 162: 105585.
• Mina, John G. M., Charlton, Rebecca L., Alpizar-Sosa, Edubiel, Escrivani, Douglas O., Brown, Christopher, Alqaisi, Amjed, Borsodi, Maria Paula G., Figueiredo, Claudia P., de Lima, Emanuelle V., Dickie, Emily A., Wei, Wenbin, Coutinho-Silva, Robson, Merritt, Andy, Smith, Terry K., Barrett, Michael P., Rossi-Bergmann, Bartira, Denny, Paul W. & Steel, Patrick G. (2021). Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase. ACS Infectious Diseases 7(1): 47-63.
• Gu, X., Brennan, A., Wei, W. Guo, G. & Lindsey, K. (2020). Vesicle transport in plants: A revised phylogeny of SNARE proteins. Evolutionary Bioinformatics 16: 1-11.
• Wan, Ying-Wooi, Al-Ouran, Rami, Mangleburg, Carl G., Perumal, Thanneer M., Lee, Tom V., Allison, Katherine, Swarup, Vivek, Funk, Cory C., Gaiteri, Chris, Allen, Mariet, Wang, Minghui, Neuner, Sarah M., Kaczorowski, Catherine C., Philip, Vivek M., Howell, Gareth R., Martini-Stoica, Heidi, Zheng, Hui, Mei, Hongkang, Zhong, Xiaoyan, Kim, Jungwoo Wren, Dawson, Valina L., Dawson, Ted M., Pao, Ping-Chieh, Tsai, Li-Huei, Haure-Mirande, Jean-Vianney, Ehrlich, Michelle E., Chakrabarty, Paramita, Levites, Yona, Wang, Xue, Dammer, Eric B., Srivastava, Gyan, Mukherjee, Sumit, Sieberts, Solveig K., Omberg, Larsson, Dang, Kristen D., Eddy, James A., Snyder, Phil, Chae, Yooree, Amberkar, Sandeep, Wei, Wenbin, Hide, Winston, Preuss, Christoph, Ergun, Ayla, Ebert, Phillip J., Airey, David C., Mostafavi, Sara, Yu, Lei, Klein, Hans-Ulrich, Carter, Gregory W., Collier, David A., Golde, Todd E., Levey, Allan I., Bennett, David A., Estrada, Karol, Townsend, T. Matthew, Zhang, Bin, Schadt, Eric, De Jager, Philip L., Price, Nathan D., Ertekin-Taner, Nilüfer, Liu, Zhandong, Shulman, Joshua M., Mangravite, Lara M. & Logsdon, Benjamin A. (2020). Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports 32(2): 107908.
• Kukharsky, Michail S., Ninkina, Natalia N., An, Haiyan, Telezhkin, Vsevolod, Wei, Wenbin, Meritens, Camille Rabesahala de, Cooper-Knock, Johnathan, Nakagawa, Shinichi, Hirose, Tetsuro, Buchman, Vladimir L. & Shelkovnikova, Tatyana A. (2020). Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice. Translational Psychiatry 10(1): 171.
• Granai, Massimo, Mundo, Lucia, Akarca, Ayse U., Siciliano, Maria Chiara, Rizvi, Hasan, Mancini, Virginia, Onyango, Noel, Nyagol, Joshua, Abinya, Nicholas Othieno, Maha, Ibrahim, Margielewska, Sandra, Wi, Wenbin, Bibas, Michele, Piccaluga, Pier Paolo, Quintanilla-Martinez, Leticia, Fend, Falko, Lazzi, Stefano, Leoncini, Lorenzo & Marafioti, Teresa (2020). Immune landscape in Burkitt lymphoma reveals M2-macrophage polarization and correlation between PD-L1 expression and non-canonical EBV latency program. Infectious Agents and Cancer 15(1): 28.
• Elmetwali, Taha, Salman, Asmaa, Wei, Wenbin, Hussain, Syed A., Young, Lawrence S. & Palmer, Daniel H. (2020). CD40L membrane retention enhances the immunostimulatory effects of CD40 ligation. Scientific Reports 10(1).
• Lai, Sook Ling, Tan, May Leng, Hollows, Robert J., Robinson, Max, Ibrahim, Maha, Margielewska, Sandra, Parkinson, E. Kenneth, Ramanathan, Anand, Zain, Rosnah Binti, Mehanna, Hisham, Spruce, Rachel J., Wei, Wenbin, Chung, Ivy, Murray, Paul G., Yap, Lee Fah & Paterson, Ian C. (2019). Collagen Induces a More Proliferative, Migratory and Chemoresistant Phenotype in Head and Neck Cancer via DDR1. Cancers 11(11): 1766.