CHEM3211: BIOACTIVE CHEMISTRY 3

• Core Chemistry 2 (CHEM2012).

• None.

• Core Chemistry 3 (CHEM3012) or Chemical Physics 3 (CHEM3411)

• To develop the fundamentals of chemistry through in-depth discussion of selected areas likely to be of most interest to students studying at the interface between chemistry and biology.

• Pericyclic transformations in synthetic organic chemistry.
• Reactive intermediate in organic processes.
• Selectivity in organic transformations
• Molecular biophysics.
• Applied spectroscopy.

Subject-specific Knowledge:

• employ advanced methods of organic synthesis alongside more basic methodologies learnt in earlier years to solve problems in organic chemistry;
• describe synthetically useful free radical reactions, carbenes, nitrenes and ionic rearrangements;
• describe methods for introducing stereoselectivity into a variety of organic reactions;
• understand biomolecular systems and explain biological function in terms of molecular structure, structural organization, and dynamic behaviour.

Subject-specific Skills:

• Interpret simple 2D NMR spectra and use this evidence in the elucidation of molecular structure using a combination of techniques;

Key Skills:

• Self-motivation, in self-guided learning.

• Lectures are used to convey concepts, demonstrate what is required to be learned and the application of the theory to practical examples. When appropriate, lectures will be supported by written material, or by information and relevant links on DUO.
• Private study should be used by students to develop their subject-specific knowledge and self-motivation, through reading textbooks and literature.
• Workshops are groups of students where problems are considered and common difficulties shared. This ensures that students have understood the work and can apply it to real life situations. These are formatively assessed. Workshops are also used to teach applied spectroscopy, where a concept is introduced and students work to understand its application and use.
• Student performance will be summatively assessed through an examination. Examinations test students' ability to work under pressure under timed conditions, to prepare for examinations and direct their own programme of revision and learning and develop key time management skills. The examination will provide the means for students to demonstrate the acquisition of subject knowledge and the development of their problem-solving skills.

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