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Physical Organic and Assembly

Using physical organic chemistry to study mechanisms, dynamics, binding, self-assembly and non-covalent interactions with a focus on gaining quantitative, molecular level understanding of properties and structure-reactivity relationships.

We apply the understanding that we gain to determine the mechanisms of organic and biological systems, develop new synthetic and catalytic methodologies, and design sensors and materials, such as gels, molecular materials, bioconjugates and diagnostic tools. With state of the art analytical facilities and instruments.
About Us

Physical Organic and Assembly

Molecular assembly and function in organic molecules and materials. Molecular properties and reactivities are tailored through gaining fundamental (quantitative) understanding using photophysical, computational, kinetic, supramolecular and crystallographic techniques to inform synthesis of new molecules, materials and processes.

1. Exploit cutting edge kinetic analysis for operando delineation of mechanisms and predicting reactivity patterns in areas including chiral quaternary ammoniums, reactivity scales of carbenes and phosphorylation reactions;

2. Deliver quantitative understanding of the intermolecular interactions underpinning self-assembly processes;

3. Apply our understanding to new chemistries including enzyme cofactors, industrial biocatalysts and designer crystallisations.

 

Members

Research Grouping Leader: Dr David Hodgson

Prof. Martin R. Bryce, Dr Mark A. Fox, Dr David R.W. Hodgson, Dr Matthew O. Kitching, Dr Paul R. McGonigal, Prof. AnnMarie C. O'Donoghue, Prof. David Parker, Prof. Graham Sandford, Prof. Jonathan W. Steed, Prof. Gareth Williams, Dr D. S. Yufit.